The critical residues of helix 5 for in vitro pentamer formation and stability of the papillomavirus capsid protein, L1.
نویسندگان
چکیده
The mono-site mutations of the absolutely conserved residues, (464)LGR(466), in the α-helix 5 (h5) of HPV16 L1 completely disrupted the pentamer formation. The implication of this finding is the potential usage of a h5-like peptide as the reagent to interfere with the pentamer formation and stability as an anti-HPV reagent.
منابع مشابه
The Critical Residues of Helix 5 for in vitro Pentamer Formation and Stability of Papillomavirus Capsid Protein, L1
Please note that technical editing may introduce minor changes to the text and/or graphics, which may alter content. The journal’s standard Terms & Conditions and the Ethical guidelines still apply. In no event shall the Royal Society of Chemistry be held responsible for any errors or omissions in this Accepted Manuscript or any consequences arising from the use of any information it contains. ...
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ورودعنوان ژورنال:
- Molecular bioSystems
دوره 10 4 شماره
صفحات -
تاریخ انتشار 2014